Showing posts with label LTP. Show all posts
Showing posts with label LTP. Show all posts

Monday, May 18, 2009

Neocortical mechanisms in motor learning



by
Jerome N Sanes

- Incontrovertible evidence: Many neocortical regions, including the motor-related areas, exhibit plasticity and are likely to contribute to motor- skill learning.

Leaning mechanisms

- Candidate mechanisms include fundamental modification in neural-spiking properties, the formation of new intrinsic or extrinsic synaptic contacts, the long-term potentiation or long-term depression of network synapses, and changes in intracortical processing.

- LTP and LTD have been proposed as mechanisms for learning and memory functions throughout the brain, although definitive proof of the relationship between synaptic plasticity and learning often is lacking.

Friday, March 13, 2009

Economodulation

Stock price is going up for several days in a row.
I am hoping it is not short-term like PTP, but rather it continues for a longer term like LTP.

I know that just a single bad news can negate this sustained increase and immediately brings it down to the bottom or the basal level, just like DSI does on VSI-VFN synapse.

One good news can produce a transient increase in stock market, just like DSI does.
I call it "heteroeconomic facilitation."
The effects of a breaking news is bidirectional, sometimes biphasic, depending on the timing and state of the market.

Unlike synaptic strength though, the problem in market price is that we don't know where the bottom lies.

Reference: Sakurai and Katz (2009)